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Updated: May 20, 2025

Use of Single Chain MHC Technology to Investigate Co-agonism in Human CD8+ T Cell Activation
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基于STING激动剂的ER向分子促进抗原交叉呈现

Xiafeng Wang1,2, Zhangping Huang2, Lixiao Xing3

  • 1Department of Laboratory Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

Nature
|March 27, 2025
PubMed
概括

研究人员开发了基于STING激动剂的ER向分子 (SABER),以增强CD8+T细胞的反应. 这种新型的输送系统向细胞内膜网,提高了疫苗对瘤和感染的疗效.

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