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Updated: May 20, 2025

Defining Substrate Specificities for Lipase and Phospholipase Candidates
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对脂质链长度选择性和FFA2的全调节的结构性见解

Mai Kugawa1,2, Kouki Kawakami1, Ryoji Kise3

  • 1Research Center for Advanced Science and Technology, The University of Tokyo, Meguro, Tokyo, Japan.

Nature communications
|March 27, 2025
PubMed
概括

研究人员使用合成配体阐明了自由脂肪酸受体2 (FFA2) 的结构机制. 这揭示了不同的分子如何激活或抑制FFA2,帮助未来的药物设计用于代谢和免疫疾病.

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