左心室喷射分数是长期传导系统节奏后心脏表现的决定因素,在患有左束枝分支阻塞的患者?
Zhu-Lin Ma1,2, Cheng-Ming Ma1, Yi-Heng Yang1
1Department of Cardiology, The First Affiliated Hospital of Dalian Medical University, No. 222. Zhongshan Road, Dalian, Liaoning Province, China.
BMC cardiovascular disorders
|March 27, 2025
概括
导电系统节奏 (CSP) 是一个安全和可行的选择,为患者与左捆分支阻塞 (LBBB) 和心力衰竭 (HF),改善心脏性能. 然而,在严重减少左心室喷射分数 (LVEF) <25%的患者中,结果不那么有利.
科学领域:
- 心脏病学 心脏病学
- 电力生理学 电力生理学
- 心脏衰竭管理的管理
背景情况:
- 患有心力衰竭 (HF) 的患者的左捆支部阻塞 (LBBB) 通常会导致失同和心脏功能受损.
- 心脏再同步治疗 (CRT) 适用于一些患者,但导电系统节奏 (CSP) 提供了一个替代方法.
- 在患有LBBB和不同程度的左心室喷射分数 (LVEF) 的患者中,CSP的疗效需要进一步调查.
研究的目的:
- 评估CSP的可行性,安全性和临床性能,在LBBB和LVEF≤35%的候选CRT患者中进行CSP.
- 为了比较患有LVEF<25%和患有LVEF在25-35%之间的患者在CSP后的心脏性能改善.
主要方法:
- 在2018年1月至2021年12月期间,连续一系列的LVEF≤35%和LBBB满足CRT标准的患者接受了CSP.
- 根据LVEF,患者被分为两组:<25%和25-35%.
- 临床结果,包括节奏响应,逆向重塑和心力衰竭再住院,在两组之间进行了比较.
主要成果:
- 在92.5%的患者中,CSP成功植入.
- 两组LVEF在CSP后的LVEF,LVEDD,LVESV,NYHA类和QRS持续时间均显著改善.
- 与LVEF<25%的患者相比,25-35%的LVEF患者显示出更高的最终LVEF和LVESV,以及较低的心力衰竭再住院率.
结论:
- CSP是一种可行的和安全的策略,用于改善LBBB和心力衰竭患者的临床结果.
- 虽然CSP有利于LVEF<25%的患者,但与LVEF25-35%的患者相比,结果不太理想.
- 及时的CSP干预可能有利于LBBB患者的心脏表现.
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