传统高流量鼻管与 extubated 患者的双重高流量鼻管的比较:一个随机交叉试验
Ravindranath Tiruvoipati1,2,3, Mallikarjuna Ponnapa Reddy4,5,6,7, Eldho Paul8
1Department of Intensive Care, Peninsula Health, Frankston, VIC, 3199, Australia. travindranath@hotmail.com.
杜埃特高流量鼻腔管 (HFNC) 显示出与常规HFNC相比的气体交换,耐受性和舒适性. 需要进一步的研究来探索Duet HFNC的更高的流速和更长的持续时间.
科学领域:
- 关键护理医学 关键护理医学
- 呼吸系统疗法 呼吸系统疗法
- 医疗器械 医疗器械
背景情况:
- 高流量鼻腔管 (HFNC) 是重症监护室 (ICU) 输送氧气的标准.
- 一个新的Duet HFNC配置提供了潜在的更高压力和改进的气体交换.
- 关于Duet HFNC的性能,安全性和患者舒适性的临床数据有限,特别是在特定的患者子组中.
研究的目的:
- 为了比较Duet HFNC与传统HFNC的临床性能,气体交换,患者耐受性和舒适性.
- 评估HFNC两种类型在鼻胃管患者和男性和女性患者之间的表现.
主要方法:
- 进行了一项单中心,开放标签,随机交叉研究.
- 输入式通风患者被随机分为接受Duet HFNC接下来是传统的HFNC,或者反之,每一个30分钟.
- 亚组分析包括带/没有鼻胃管的患者和男性/女性患者. HFNC 流量标准为 40 L/min,具有相同的 FiO2.2.
主要成果:
- 在Duet和传统HFNC之间,在氧化 (PaO2),二氧化碳水平 (PaCO2) 或氧和 (SaO2) 中没有发现显著差异.
- 两种HFNC类型的患者舒适性和耐受性也相似.
- 亚组分析显示,基于鼻胃管的存在或患者的性别,性能没有显著差异.
结论:
- 在这个患者群体中,Duet HFNC的临床性能与传统的HFNC相当.
- 对Duet HFNC的更高流速和扩展使用的进一步调查是有必要的,以充分确定其临床实用性.
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