不同局部麻醉方法的对比,用于静脉内注射:一个随机交叉研究
Jeffrey Man Yeung Lo1,2, Veronica Yui Yan Li3, Rachel Ka Ying Cheung4,3
1Department of Ophthalmology, Grantham Hospital, Hong Kong SAR, China. lmy887@ha.org.hk.
International journal of retina and vitreous
|March 27, 2025
概括
在局部麻醉剂滴剂中添加普拉巴卡因 pledget 并没有显著减少静脉内注射 (IVI) 期间的疼痛. 然而,这种辅助麻醉剂可能会改善接受IVI治疗的先前未接受治疗的患者的疼痛管理.
科学领域:
- 眼科医生 眼科 眼科
- 麻醉学 麻醉学
背景情况:
- 静脉内注射 (IVI) 是一种常见的眼科手术.
- 在IVI期间的疼痛管理对于患者的舒适性和遵守性至关重要.
- 局部布拉卡因经常使用,但其疗效可能会提高.
研究的目的:
- 为了研究一支浸泡在普拉巴卡因的pledget与局部普拉巴卡因滴剂在IVI期间减轻疼痛的辅助作用.
- 用视觉模拟尺度 (VAS) 和问卷来评估患者报告的疼痛水平.
主要方法:
- 一个单中心,前性,随机,双盲交叉研究,涉及60名接受IVI治疗的患者.
- 患者接受了标准的局部0.5%普拉巴卡因滴.
- 干预组在交叉设计中接受了0.5%的甲浸泡的诺言或正常的液浸泡的诺言 (安慰剂).
- 使用VAS和问卷在注射后立即,10分钟和20分钟间隔评估疼痛.
主要成果:
- 在任何时间点 (p > 0.05) 中,在甲承诺组和安慰剂组之间没有观察到疼痛强度的统计学上显著差异.
- 在注射后立即,10分钟和20分钟,安慰剂组的疼痛得分始终较低,尽管没有显著的.
- 一个小组分析表明,以前没有接受过治疗的患者可能会在添加甲 pledget时感到疼痛减少.
结论:
- 与用于静脉内注射的局部普拉卡因单独滴剂相比,添加浸泡在普拉卡因中的保证剂的辅助使用并没有显著改善疼痛缓解.
- 这些发现表明,对以前没有接受过治疗的患者来说,有潜在的益处,需要进一步调查.
- 目前对IVI的麻醉方案可能不需要为大多数患者添加普拉巴卡因.
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