额头内侧的高静止症和疾病控制与额头骨厚度的关联在壮症中
Ihsan Ayhan1, Ömercan Topaloğlu2, Taner Bayraktaroğlu2
1Internal Medicine Clinics, Zonguldak Atatürk State Hospital, Zonguldak, Türkiye, Turkey. ihsanayhan@hotmail.com.
BMC endocrine disorders
|March 27, 2025
概括
额头内侧高静止症 (HFI) 在壮症中很常见,并与额头骨厚度 (FBT) 的增加有关. HFI和骨厚度的变化似乎独立于疾病活动,这表明基线成像评估.
科学领域:
- 内分泌学 在内分泌学.
- 放射学 放射学是一门学科.
- 神经外科 神经外科
背景情况:
- 额头内侧缩 (Hyperostosis frontalis interna,简称HFI) 是一种状况,其特征是额头骨的内表变厚.
- 有限的研究已经研究了HFI在患有巨病的患者.
- 巨症是一种由生长激素过量引起的疾病,可以导致各种骨变化.
研究的目的:
- 为了调查HFI在壮病患者中的患病率.
- 评估HFI和额头骨厚度 (FBT) 之间的关联.
- 为了探索疾病控制和骨厚度在壮病之间的关系.
主要方法:
- 成年壮症患者根据基线MRI的HFI的存在 (组2) 或缺乏 (组1) 被分为两组.
- 测量了额头,头骨和骨的厚度 (FBT,PBT,OBT).
- 分析了随着时间的推移骨厚的变化以及与疾病控制状态的关联.
主要成果:
- 在52名壮病患者中,29名患者有HFI.
- 与没有HFI (2组) 的患者相比,HFI患者的FBT,PBT和OBT显著更高 (组1).
- 骨厚度在HFI患者中呈现持续增加,并且独立于壮症疾病活性.
结论:
- HFI是壮病患者常见的发现.
- 高血压与头骨骨厚度的增加和持续增长有关.
- 骨厚度及其在壮症中的进展似乎与疾病活动无关,这突显了基线成像对评估的重要性.
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