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Updated: May 20, 2025

Hyperinsulinemic-euglycemic Clamps in Conscious, Unrestrained Mice
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类似葡萄糖-1受体激活剂对精神疾病的影响:来自孟德尔随机化研究的证据

Longgang Xiang1, Ying Peng1

  • 1State Key Laboratory of Bioactive Substances and Functions of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100050, China.

International journal of molecular sciences
|March 27, 2025
PubMed
概括

类似葡萄糖-1受体激动剂 (GLP1RA) 显示出与降低精神分裂症风险的潜在因果关系,可能由身体质量指数 (BMI) 介导. 这项研究发现GLP1RA的证据不足.

关键词:
作为GLP1R的激动剂.门德尔的随机化药物目标是药物目标.全基因组关联研究研究.精神疾病 精神疾病

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Studying the Hypothalamic Insulin Signal to Peripheral Glucose Intolerance with a Continuous Drug Infusion System into the Mouse Brain08:32

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