根据酒精摄入量和吸烟,轮班工作与急性冠状动脉综合征之间的关联
Seok-Jin Ryu1,2, Sun-Min Kim3, Hyun-Yi Kook4
1Department of Emergency Medicine, Chonnam National University Hospital, Gwangju 61469, Republic of Korea.
轮班工作增加了急性冠状动脉综合征 (ACS) 的风险,特别是对于非吸烟者. 针对生活方式和职业因素的有针对性的工作场所干预对于预防轮班工人中ACS至关重要.
科学领域:
- 职业健康 职业健康 职业健康
- 心血管流行病学心血管流行病学
- 公共卫生 公共卫生
背景情况:
- 轮班工作与急性冠状动脉综合征 (ACS) 风险增加有关.
- 轮班工人经常表现出更高的吸烟和酒精消费率.
- 轮班工作,吸烟和酒精对ACS风险的相互作用需要进行调查.
研究的目的:
- 检查吸烟和饮酒对轮班工作和ACS风险之间的关系的影响.
- 确定有助于轮班工人中ACS发病率的特定风险因素和相互作用.
主要方法:
- 利用韩国基因组和流行病学研究 (KoGES) 的数据.
- 雇员考克斯比例回归和相互作用分析,以评估轮班工作,吸烟和饮酒对ACS发生率.
- 定义ACS为2003年至2020年间诊断的心肌梗塞或胸痛.
主要成果:
- 轮班工作与ACS风险增加1.74倍相关 (HR1.74,95% CI 1.20,2.53).
- 单单吸烟和饮酒并没有显示出与ACS有显著的独立关联.
- 轮班工作在不吸烟者中显著增加了ACS风险 (HR 2.26,95% CI 1.44,3.55),具有显著的相互作用效应 (p < 0.01).
结论:
- 轮班工作是ACS的独立风险因素,特别明显的是非吸烟者.
- 干预措施应解决轮班工人的职业安排和生活方式的改变.
- 建议包括优化班次,定期进行心血管检查,促进健康习惯和戒烟资源.
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