在保加利亚测量高血压患者的坚持 - 试点研究与适当药物使用尺度的自我效能
Zornitsa Mitkova1, Elena Dimitrova2, Velislava Kazakova1
1Department of Organization and Economy of Pharmacy, Faculty of Pharmacy, Medical University Sofia, 1000 Sofia, Bulgaria.
Medicina (Kaunas, Lithuania)
|March 27, 2025
概括
在保加利亚,高血压药物的服药量一般很好,但年龄较大,多种疾病和大量处方会对患者的服药性产生负面影响. 固定剂量组合 (FDCs) 显示出与多种单药疗法相比,可比或更好的坚持.
科学领域:
- 心脏病学 心脏病学
- 公共卫生 公共卫生
- 药理学 药理学是指药理学的学科.
背景情况:
- 高血压是保加利亚的主要心血管疾病,对公众健康构成重大挑战.
- 患者不遵守药物治疗是管理高血压的常见问题.
- 对高血压的有效管理和改善患者的治疗结果,评估坚持是至关重要的.
研究的目的:
- 评估保加利亚高血压患者的药物服药程度.
- 使用经过验证的适合药物使用量表 (SEAMS) 进行依从性评估.
- 确定影响保加利亚高血压患者服药的因素.
主要方法:
- 在保加利亚索非亚和布尔加斯的主要心脏病中心进行的一项横截面研究.
- 从2024年1月到7月从232名高血压患者收集的数据.
- 使用的SEAMS (19个问题) 的保加利亚语验证版本,使用了统计分析,包括Cronbach的α,ANOVA,Pearson相关性和共变性测试.
主要成果:
- 共有232名患者 (49.6%的男性,50.4%的女性) 完成了这项研究.
- 增加的并发症和处方药物的数量与较低的坚持水平相关.
- 年龄较大对坚持得分产生了负面影响;固定剂量组合 (FDC) 与多个单一产品相比,在几个年龄组中显示出类似或更好的坚持.
结论:
- 按照SEAMS的测量,高血压的保加利亚人群中的药物坚持通常是好的.
- 负面影响坚持的因素包括老年,多药性和并发症.
- 与FDC相比,单一产品治疗在某些年龄人口统计学中与较差的坚持有关.
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