在人类中的物种感染 - - 一个叙述性回顾
Anastasia Vasilopoulou1, Takis Panayiotou1, Stella Baliou1
1School of Medicine, University of Crete, 71003 Heraklion, Greece.
Microorganisms
|March 27, 2025
概括
在囊性纤维化患者中,越来越多地发现Inquilinus物种,特别是Inquilinus limosus的感染. 碳烯是有效的治疗方法,死亡率仍然很低.
科学领域:
- 医学微生物学 医学微生物学
- 传染性疾病 传染性疾病
- 临床诊断 临床诊断 临床诊断
背景情况:
- Inquilinus物种是越来越多地在患者中发现的格拉姆阴性棒,特别是患有囊性纤维化的人.
- 这些细菌的特点是特定的生化和生长特性,包括酶阳性和1%NaCl的生长.
研究的目的:
- 审查所有报告的因Inquilinus物种引起的人类感染.
- 分析流行病学数据,抗菌素耐药性模式,治疗结果和死亡率.
主要方法:
- 使用PubMed/MedLine和Scopus数据库进行了叙事文献综述.
- 分析了来自25名患者的13篇文章的数据.
主要成果:
- 囊性纤维化是主要的危险因素 (92%),呼吸道感染是最常见的 (96%).
- 主要的物种是Inquilinus limosus,通常是多微生物感染的一部分 (77.3%).
- 该病原体对β-乳酸盐 (除了卡巴胺) 呈现耐药性,这是最常见的治疗方法,与类和氨基甘油一起. 死亡率很低 (4%).
结论:
- 在对β-lactams无反应的呼吸道感染或具有多微生物感染的囊性纤维化患者的差异诊断中应考虑Inquilinus物种.
- 微生物识别的困难,通常需要像16srRNA测序这样的分子技术,需要临床和实验室的意识.
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