在肥胖患者中用保存的喷射分数诊断心力衰竭
Marino Basha1, Evdoxia Stavropoulou1, Anastasia Nikolaidou1
11st Department of Cardiology, AHEPA Hospital, School of Medicine, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
Journal of clinical medicine
|March 27, 2025
概括
由于成像挑战和改变的生物标志物,在肥胖患者中诊断心力衰竭与保存的喷射分数 (HFpEF) 很困难. 本综述为在各种临床场景中对肥胖个体进行准确的HFpEF诊断提供了洞察力.
科学领域:
- 心脏病学 心脏病学
- 肥胖医学 肥胖医学
背景情况:
- 肥胖是一种流行病,与心力衰竭 (HF) 风险的增加有关,特别是心力衰竭与保留喷射分数 (HFpEF) 的风险.
- 诊断HFpEF是复杂的,因为微妙的心脏重塑,腹功能障碍,和左心室 (LV) 填充压力升高.
研究的目的:
- 为准确诊断肥胖患者的HFpEF提供见解.
- 在特定的临床场景中解决诊断挑战,包括肥胖,心房动 (AF) 和肺高血压 (PH).
主要方法:
- 对HFpEF的当前文献和诊断算法的审查.
- 多模式成像和临床评估的应用.
主要成果:
- 肥胖使HFpEF诊断复杂化,因为心声回声低于最佳,BSA指数参数低估,和改变的尿素 (NP) 值.
- 肥胖患者的AF和PH等同时存在的疾病进一步挑战了透支功能障碍的评估.
结论:
- 在肥胖患者中,准确的HFpEF诊断需要量身定制的方法,考虑到成像质量和生理变化.
- 多模式成像和精细的诊断算法对于管理高风险人群中的HFpEF至关重要.
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