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使用创新的模拟方法提高谷氨的口服生物可用性

Naibo Yin1, Paul W R Harris2,3, Mengyang Liu1,3

  • 1School of Pharmacy, Faculty of Medical and Health Sciences, The University of Auckland, 85 Park Road, Grafton, Auckland 1023, New Zealand.

Pharmaceutics
|March 27, 2025
PubMed
概括

化学改性谷氨 (GSH) 类似物是为了改善口服生物可用性而开发的. 一种N-甲基化衍生物,化合物1.70,显著提高了血半衰期和生物可用性,表明了治疗潜力.

关键词:
类似的同类产品抗氧化剂是一种抗氧化剂.化学修饰是一种化学修饰.谷氨 (GSH) 的使用.口服生物可用性 口服生物可用性酸合成的合成

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