Mandragora autumnalis 分布,植物化学特征和药理学生物活性
Ghosoon Albahri1,2, Adnan Badran3, Zaher Abdel Baki4
1Doctoral School of Science and Technology-Platform of Research and Analysis in Environmental Sciences (EDST-PRASE), Beirut P.O. Box 657314, Lebanon.
Pharmaceuticals (Basel, Switzerland)
|March 27, 2025
概括
传统医学中使用的一种植物Mandragora autumnalis含有具有抗氧化,抗微生物和抗癌特性的植物化学物质. 需要进一步的研究来确认其治疗潜力和对各种疾病的安全性.
科学领域:
- 民族植物学和植物化学.
- 药理学和毒理学 药理学和毒理学
背景情况:
- 曼德拉戈拉 (曼德拉格) 属因其在草药治疗中的历史用途及其丰富的神话联系而闻名.
- 曼德拉戈拉物种,特别是M. autumnalis,在地中海和喜马拉雅地区的传统医学中得到了广泛的应用.
研究的目的:
- 综合审查和更新关于Mandragora autumnalis治疗功能的信息.
- 详细介绍M. autumnalis的药理活动和植物化学成分,这些都与治疗糖尿病,癌症和心脏病有关.
主要方法:
- 在主要的科学数据库 (PubMed,Scopus,ScienceDirect等) 进行系统的文献搜索. 和谷歌学者/谷歌.
- 搜索侧重于1986年至2023年间发表的文章.
- 对植物学,生态学,植物化学和药理学数据的审查,包括毒理学影响.
主要成果:
- 秋季植物含有多种植物化学物质,包括库马林,维他诺化物和化物,有助于其药理作用.
- 已证明的活动包括抗炎作用,自由基清除,抗菌作用和对癌细胞系的细胞毒性作用.
- 这种植物表现出酶抑制性质 (胆酶,铁酶,α-氨酶,α-葡萄糖酶),并且在控制代谢风险因素方面表现出潜力.
结论:
- 秋季是一种有价值的新生物活性化合物来源,具有显著的治疗潜力.
- 这种植物具有抗氧化,抗微生物,抗糖尿病和抗癌性质,对正常细胞系的细胞毒性较低.
- 进一步的研究是必要的,以验证有效性,确保安全性,并阐明其治疗应用的分子作用机制.
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