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塞夫特里亚克松载脂体纳米颗粒用于肺部输送,用于治疗下呼吸道感染:开发和表征

Vijay Kumar Panthi1, Kathryn E Fairfull-Smith2,3, Timothy J Wells4,5

  • 1Pharmacy Discipline, School of Clinical Sciences, Faculty of Health, Queensland University of Technology (QUT), Brisbane, QLD 4000, Australia.

Pharmaceuticals (Basel, Switzerland)
|March 27, 2025
PubMed
概括

我们开发了含有 ceftriaxone (CTX) 的脂质体纳米颗粒,用于治疗抗性下呼吸道感染 (LRTI). 这些吸入的纳米颗粒显示出有希望的气溶液和长时间的药物释放,以有效的肺部输送.

关键词:
塞夫特里亚克松是什么意思干粉吸入器配方 干粉吸入器配方脂质体组是什么? 脂质体组是什么?下呼吸道感染 下呼吸道感染纳米颗粒是一种纳米粒子.

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The human respiratory tract, comprising the upper and lower segments, serves as a critical interface with the external environment. The upper respiratory tract (URT)—including the nostrils, sinuses, pharynx, and oropharynx—is heavily colonized by microbes, while the lower respiratory tract (LRT), composed of the larynx, trachea, bronchi, and lungs, was long thought to be sterile. However, recent molecular studies have revealed that the lungs are not devoid of microbes but act more...
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