三糖糖和腰部高度比率与中风之间的关联:一个基于人口的研究
Fangyuan Xu1, Xingxing Su2, Fan Dai1
1The First Clinical Medical School, Anhui University of Chinese Medicine, Hefei, China.
Frontiers in endocrinology
|March 27, 2025
概括
甘油三糖-腰高度比率 (TyG-WHtR) 与更高的中风风险有关. 提升的TyG-WHtR可能有助于预测中风,有助于早期预防和干预策略.
科学领域:
- 心血管健康 心血管健康
- 代谢综合征研究 代谢综合征研究
- 公共卫生流行病学 流行病学
背景情况:
- 脑卒中是全球主要的健康问题.
- 甘油三糖-腰高度比 (TyG-WHtR) 在评估健康风险方面显示出有前途.
- 关于TyG-WHtR与中风发病率之间的具体联系的研究有限.
研究的目的:
- 调查TyG-WHtR水平与中风之间的关联.
- 评估TyG-WHtR作为潜在的中风风险生物标志物.
- 分析来自国家健康和营养检查调查 (NHANES) 的数据.
主要方法:
- 分析了来自NHANES (2011-2018) 的8757名参与者.
- 多变量逻辑回归和平滑曲线适配,以评估TyG-WHtR-中风关系.
- 分析子组,灵敏度和ROC曲线以确认发现并比较预测值.
主要成果:
- 在较高的TyG-WHtR和中风发生率增加 (OR:1.26) 之间发现了积极的关联.
- 每个单位的TyG-WHtR增加都与26%更高的中风概率相关.
- 与TyG指数相比,TyG-WHtR表现出优越的预测能力.
结论:
- 提升的TyG-WHtR水平与中风患病率的增加有关.
- TyG-WHtR可以作为一种有价值的中风风险预测工具.
- 这些发现支持TyG-WHtR在临床中风预防和早期干预方面的潜在作用.
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