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COVID-19和帕金森病类似症状之间的潜在关联

Taketomo Maruki¹, Shinichiro Morioka¹, Satoshi Kutsuna²

¹Disease Control and Prevention Center, National Center for Global Health and Medicine, Tokyo, Japan.

|March 27, 2025

概括

COVID-19幸存者报告了诸如失眠和勃拉迪基尼西亚之类的神经症状. 虽然一些症状持续存在,但没有参与者在感染后被诊断出患有帕金森病,因此需要进一步调查.

科学领域:

神经学神经学
传染性疾病传染性疾病
流行病学流行病学

背景情况:

帕金森病 (PD) 的病因是复杂的,病毒感染是潜在的,虽然不完全理解的,贡献因素.
新出现的证据表明,COVID-19后的情况和神经系统的后果之间可能存在联系,需要进一步研究潜在的长期影响.

研究的目的:

调查个人从COVID-19中康复后经历的神经症状.
探索后COVID-19条件和帕金森病类似症状的发展之间的潜在关联.

主要方法:

在2020年2月至2021年11月期间,在从COVID-19中康复并参加门诊服务的患者中进行了问卷调查.
收集了人口和临床数据,包括COVID-19后疾病的存在和持续时间.

主要成果:

失眠是最常见的症状 (27.9%),其次是布拉迪基尼西亚 (13.1%).
布拉迪基尼西亚的平均持续时间为90天,3.6%的参与者报告持续超过180天.
其他报告的症状包括 (9.1%),静止 (5.0%),便秘 (4.8%) 和昏睡 (2.8%),很少持续超过180天. 没有报告PD,痴呆症或其他神经系统疾病的新诊断.

结论:

虽然COVID-19可以导致持续的神经症状,如布拉迪基尼西亚,但在这个群体中没有与帕金森病发展的直接因果关系.
纵向研究对于充分阐明COVID-19感染与长期患帕金森病或相关神经疾病的风险之间的关系至关重要.

关键词:

帕金森病 (PD) 是一种疾病.神经学后续情况后COVID-19 条件后的COVID-19 条件

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