在肺移植接受者乳房植入物感染的Candida dubliniensis
Ashley Barnes1, Kristen Broderick2, Errol Bush3
1Division of Infectious Disease, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland.
JHLT open
|March 27, 2025
概括
一名肺移植患者在接受抗真菌治疗后也出现了由Candida dubliniensis引起的持续性乳房植入物感染. 这一案例强调了在诊断和管理这种罕见感染时,需要进行彻底的手术培养.
科学领域:
- 医学案例报告 病例报告
- 传染性疾病 传染性疾病
- 移植手术 移植手术
背景情况:
- 肺移植接受者可能容易感染机会性感染.
- 用植入物进行乳房重建,在移植后的感染管理方面存在独特的挑战.
- 捐赠者传播的感染虽然很少见,但会带来很大的风险.
研究的目的:
- 报告肺移植接受者双边乳房植入物感染的罕见病例.
- 为了调查Candida dubliniensis在移植后感染中的作用.
- 强调对植入物相关真菌感染的诊断和管理策略.
主要方法:
- 一个肺移植接受者的详细临床病例介绍.
- 审查患者的病史,包括乳腺癌和重建.
- 对抗真菌治疗和感染进展的分析.
- 乳房植入物感染的微生物学研究.
主要成果:
- 患者在肺移植后出现了由捐赠者传播的Candida dubliniensis empyema.
- 尽管进行了抗真菌治疗,但发生了同样有机体的渐进性双边乳房植入物感染.
- 植入物上的生物膜形成可能阻碍了完全的抗真菌根除.
结论:
- 在免疫功能低下的患者中,Candida dubliniensis可能会导致持续的乳房植入物感染.
- 深度操作培养对于诊断和管理具有挑战性的植入物相关感染至关重要.
- 这一案例凸显了在移植后传染病管理中考虑植入物完整性的重要性.
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