在血管光滑肌细胞中化酶5的失活会加剧大动脉动脉瘤和剖析

Yuyao Feng1,2, Yunfei Xue1, Xiaohang Feng1

  • 1Department of Pathophysiology, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, PR China.

PubMed
概括

大动脉光滑肌细胞中减少的化酶5A (PDE5A) 会使大动脉动脉瘤和剖析 (AAD) 恶化. 恢复PDE5A可以防止AAD,建议在高危患者中谨慎使用PDE5A抑制剂.

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