在帕金森病中记忆,视觉空间和语言功能的神经心理测试:审查,批评和建议
Ondrej Bezdicek1, Roberta Biundo2,3, Sarai Boelema4
1Department of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine and General University Hospital in Prague, Charles University, Prague, Czech Republic.
概括
在帕金森病 (PD) 中,认知障碍很常见. 本综述建议针对记忆,语言和视觉空间功能进行特定的神经心理测试,以改善PD-MCI和PDD的诊断.
科学领域:
- 神经科学是一个神经科学.
- 神经学 神经学
- 心理学 心理学 心理学
背景情况:
- 认知障碍是帕金森病 (PD) 的一个重要的非运动并发症.
- 准确检测轻度认知障碍 (PD-MCI) 和痴呆症 (PDD) 对患者管理至关重要.
- 需要一种标准化的方法来评估PD的认知能力.
研究的目的:
- 系统地审查和评估用于评估PD-MCI和PDD的认知工具.
- 在帕金森病认知障碍中建立最佳的诊断准确性测试.
- 为认知评估工具提供专家建议.
主要方法:
- 对评估记忆,语言和视觉空间领域的测试进行系统的文献综述.
- 评估所选测试的心理测量和临床测量特性.
- 国际帕金森和运动障碍学会 (IPMDS) 专家小组对测试的评分.
主要成果:
- 审查了39项试验和48项结果措施.
- 建议进行七项测试:4项用于记忆,1项用于视觉空间,1项用于语言,1项用于病前智力.
- 10个测试是"建议有警告",11个是"建议",11个是"列出".
结论:
- 推的神经心理测试可以指导PD-MCI和PDD认知障碍的评估和进展监测.
- 这些推的测试适合在临床试验中用于参与者分层或作为结果测量.
- 新的认知措施需要进一步验证才能达到"推"状态.
相关概念视频
Parkinson's Disease: Overview
415
Neurodegenerative disorders are progressive diseases that cause irreversible damage and loss to neurons in specific brain areas. Examples of these disorders include Parkinson's disease, Alzheimer's disease, Multiple Sclerosis (MS), and Amyotrophic Lateral Sclerosis (ALS). These disorders share characteristics such as proteinopathies, selective neuronal vulnerability, and a complex interplay between genetic and environmental factors. The primary therapeutic goal for these conditions is...
415
Parkinson's Disease: Treatment
178
Neurodegenerative disorders, such as Parkinson's Disease (PD), involve the gradual and irreversible destruction of neurons in particular brain areas. These disorders exhibit standard features like proteinopathies, selective vulnerability of some neurons, and an interaction of intrinsic properties, genetics, and environmental influences in neural injury.
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
Parkinson's Disease is primarily a result of the loss of dopaminergic neurons in the substantia nigra pars compacta. The cornerstone of...
178
Neural Regulation
39.0K
Digestion begins with a cephalic phase that prepares the digestive system to receive food. When our brain processes visual or olfactory information about food, it triggers impulses in the cranial nerves innervating the salivary glands and stomach to prepare for food.
39.0K
Alzheimer's Disease: Overview
412
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
412


