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Updated: May 20, 2025

Visualization of G3BP Stress Granules Dynamics in Live Primary Cells
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伪狂犬病病毒IE180的蛋白质将G3BPs劫持到核中,以抑制压力颗粒的形成

Ruihan Zhao1, Zhenbang Zhu1, Wenqiang Wang1

  • 1Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses, College of Veterinary Medicine, Yangzhou University College of Veterinary Medicine, Yangzhou, China.

Journal of virology
|March 27, 2025
PubMed
概括

伪狂热病毒 (PRV) 蛋白IE180通过与G3BP蛋白相互作用并将其隔离到核中,从而抑制抗病毒应激颗粒 (SG) 的形成,帮助病毒复制. 这种机制对于PRV免疫逃避至关重要,并且可能与其他alphaherpesvirus共享.

关键词:
在 G3BP1/2在此之前,PRV IE180核定位的核定位压力颗粒是压力颗粒.

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