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Updated: May 20, 2025

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在炎症性肠病中进行结直肠新生病监测的内镜技术:系统性审查和网络元分析

Chih-Wen Huang^1,2,3, Hsu-Heng Yen^1,3, Yang-Yuan Chen^1,3

¹Division of Gastroenterology, Changhua Christian Hospital, Changhua, Taiwan.

United European gastroenterology journal

|March 27, 2025

概括

与标准白光内镜 (WLE) 相比,基于染料的染色内镜 (DCE) 在炎症性肠病 (IBD) 监测中显著改善了瘤检测. 在DCE无法实现的情况下,高清WLE与向活检是可行的替代方案.

科学领域:

胃肠病学胃肠病学
内镜成像系统的成像
在瘤学瘤学.

背景情况:

炎症性肠病 (IBD) 的监测传统上依赖于基于染料的染色内镜 (DCE).
内镜的进步引入了虚拟染色内镜 (VCE) 技术.
这些技术对IBD监测的比较有效性需要评估.

研究的目的:

在IBD监测中进行一个网络元分析,比较各种内镜检测神经瘤检测技术.
为了评估每位患者的瘤检测率,积极预测值 (PPV) 和停药时间.
调查活检方案对瘤检测率的影响.

主要方法:

16项随机对照试验 (2514名患者) 的网络元分析.
基于染料的染色内镜 (DCE),高清和标准清白光内镜 (WLE),i-scan,窄带成像 (NBI),灵活的光谱成像颜色增强 (FICE) 和自发光成像 (AFI) 的比较.
评估瘤检测率,PPV和退出时间,根据活检协议进行子组分析.

主要成果:

与标准定义的WLE相比,基于染料的染色内镜 (DCE) 显著增加了新生病检测率 (OR:2.56 [1.17-5.59]).
在检测率的排名中,高清WLE,NBI,FICE,i-scan和AFI紧随其后.
在DCE,VCE,高清WLE和标准定义WLE之间没有观察到PPV的显著差异,尽管DCE的戒断时间更长.
随机或向活检的DCE和向活检的高清WLE显示出比随机活检的标准定义WLE更高的检测率.

结论:

在检测IBD患者的瘤方面,DCE显著优于标准定义WLE,随机活检增强检测.
虽然DCE没有减少PPV,但它增加了手术时间.
如果DCE是不可行的,高清WLE与向活检是推的替代方案,因为其他VCE技术没有显著的优势.

关键词:

结直肠瘤是什么意思基于染料的染色体内显微镜.进行内镜技术.图像增强内镜的成像增强内镜炎症性肠病是一种炎症性肠病.瘤检测率的发现率患者监测患者监测患者监测虚拟的染色内镜是虚拟的

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