在早期持久性AF患者的冷热气球消去后减少AF负担:COOL-PER试验
So-Ryoung Lee1, Eue-Keun Choi1, Kyung-Yeon Lee2
1Department of Internal Medicine, Seoul National University Hospital, Seoul, Republic of Korea; Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Republic of Korea.
JACC. Clinical electrophysiology
|March 27, 2025
概括
化可显著降低心房 (AF) 的负担,并改善早期持久性AF患者的症状. 该程序导致许多患者的AF类型的回归,提高了他们的生活质量.
科学领域:
- 心脏病学 心脏病学
- 电子生理学 电子生理学
- 医疗器械 医疗器械
背景情况:
- 关于减少心房 (AF) 负担,AF类型回归和持续性AF的冷后症状改善的数据有限.
- 持久性AF在管理和治疗疗效方面带来了挑战.
- 了解冷处理对AF负担和类型的影响对于临床实践至关重要.
研究的目的:
- 为了评估冷剥离在减少AF负担方面的有效性.
- 为了评估冷后从持久性到发性AF的回归.
- 确定冷处理对AF相关症状和生活质量的影响.
主要方法:
- 对早期持久性AF患者 (≤3年) 的前性多中心队列研究.
- 植入式循环记录器用于冷前和冷后12个月的持续AF监测.
- 评估AF负担,AF类型,症状和生活质量,使用SF-36问卷.
主要成果:
- 化后的平均AF负担从77%降至9% (P < 0.001).
- 76%的基线持续性AF患者呈现回归至神经系统性AF或没有复发.
- 77%的患者报告说AF相关症状和生活质量有所改善.
结论:
- 结冷处理有效地减少了早期持久性AF的AF负担.
- 该程序促进AF类型的回归,导致显著的症状改善.
- 结冷处理为管理持续性AF和增强患者福祉提供了可行的治疗选择.
更多相关视频
10:46Non-fluoroscopic Catheter Tracking for Fluoroscopy Reduction in Interventional Electrophysiology
Published on: May 26, 2015
13.2K
08:00Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter
Published on: June 15, 2015
13.8K
相关概念视频
01:22Methods of reducing fever
The signs and symptoms of fever include hot and dry skin, flushed face, thirst, muscle aches, anorexia, headache, tachycardia, tachypnea, and fatigue. Elevated body temperature is reduced using two methods: pharmacological and nonpharmacological. Proper identification and treatment of the root cause of a fever is of utmost importance.
Pharmacological Methods of Reducing Fever:
Pharmacological Methods of Reducing Fever:
01:29Decreased Body Temperature
A decreased body temperature can occur in patients with hypothermia and frostbite. Heat loss with extended cold exposure overpowers the body's ability to create heat, resulting in hypothermia. Core temperature readings help classify hypothermia. Mild hypothermia is temperatures between 32 °C (89.6 °F) and 35°C (95 °F) and is caused by impaired thermoregulation. Moderate hypothermia is temperatures between 28 C (82.4 °F) and 32 °C (89.6 °F) caused by sustained extreme cold exposure, and severe...