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Updated: Jun 6, 2026

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减少MDS患者临床试验资格障碍:一个icMDS立场声明

Uma Borate1, Kelly Pugh1, Allyson Waller1

  • 1Division of Hematology, The Ohio State University Comprehensive Cancer Center/James Cancer Hospital, The Ohio State University, Columbus, OH.

Blood
|March 27, 2025
PubMed
概括

骨髓质疏松症候群 (MDS) 临床试验的限制性资格标准通常不必要地将患者排除在外. 这项研究发现,各阶段的标准相似,很少与药物安全性保持一致,阻碍了招生.

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The ability of induced pluripotent stem cells or iPSCs to differentiate into most body cell types has stimulated repair and regenerative medicine research over the past few decades. iPSC-derived blood cells, hepatocytes, beta islet cells, cardiomyocytes, neurons, and other cell types can repair injuries or regenerate damaged tissue in diseases such as diabetes and neurodegenerative disorders.