牙发育障碍在脑膜发育不良症中的疾病
Vincent R The1, Brunilda Dhamo1,2, Eppo B Wolvius1,2
1Department of Oral & Maxillofacial Surgery, Special Dental Care and Orthodontics, Erasmus University Medical Centre.
The Journal of craniofacial surgery
|March 27, 2025
概括
患有脑硬化症 (CCD) 的患者的牙发育延迟约3.3年. 这种延迟在青春期保持稳定,并且不受超数牙的数量显著影响.
科学领域:
- 遗传学和发育生物学
- 儿科牙科 儿科牙科
- 矯正牙科 矯正牙科是一種矯正牙科.
背景情况:
- 脑硬化症 (CCD) 是一种罕见的遗传疾病,影响骨发育,包括牙.
- 牙异常,如发育迟缓和多余的牙,在CCD患者中很常见.
- 了解CCD中牙发育的纵向进展对于临床管理至关重要.
研究的目的:
- 为了研究牙发育的纵向延迟,在患有结核骨张力症 (CCD) 的患者.
- 评估越来越多的牙对CCD患者牙发育延迟的影响.
主要方法:
- 一项纵向研究涉及38名参与者 (13名CCD,25名对照) 来自R代研究.
- 在两个时间点使用Demirjian方法评估牙发育.
- 线性混合模型和线性回归分析用于评估发育迟缓和多数牙的影响.
主要成果:
- 在儿童和青少年期间,牙发育减缓的速度在两组中都没有显著差异.
- 与对照组相比,CCD患者表现出大约3.3年的牙发育显著延迟,独立于性别和超数牙.
- 额外的牙的数量没有显著影响牙发育延迟的程度 (P=0.22).
结论:
- 患有cleidocranial dysplasia的个体的牙发育延迟了大约3.3年,这种延迟从青春期开始就持续了.
- 额外的牙数量似乎不会加剧CCD患者的牙发育延迟.
- 这些发现突显了CCD中延迟牙成熟的一致模式,为正牙科和儿科牙科护理策略提供了信息.
更多相关视频
02:42Analysis of Craniomaxillofacial Malformations in Mice Using Three-dimensional Microcomputed Tomography
Published on: January 17, 2025
203
10:23Author Spotlight: Three-Dimensional Cephalometric Landmark Annotation Demonstration on Human Cone Beam Computed Tomography Scans
Published on: September 8, 2023
2.6K
相关概念视频
01:15Teeth
275
The formation of teeth, also known as odontogenesis, is a complex process that begins in utero, around the sixth week of embryonic development. There are three stages to this process: the bud stage, the cap stage, and the bell stage.
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...
275
01:29Bone Disorders
3.4K
Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
3.4K
01:21Tooth Anatomy
306
The human tooth enables us to eat a variety of foods, speak clearly, and even aid in shaping our faces. Teeth are composed of various elements that work together. Here's a detailed look at the anatomy of a human tooth.
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
306
01:22Sutures of the Skull
6.0K
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
6.0K