在类风湿性关节炎中DXA和心血管疾病:范围审查
Mina Ebrahimiarjestan1, Miriam O'sullivan2, Attracta Brennan3
1Department of Industrial Engineering, Tsinghua University, Beijing, PR China; School of Medicine, University of Galway, Ireland.
概括
双能X射线吸收计 (DXA) 显示出在风湿性关节炎 (RA) 患者中评估心血管疾病 (CVD) 风险的潜力. 需要进一步的研究来探索DXA.
科学领域:
- 风湿病学和心血管健康
- 医学成像和诊断 医学成像和诊断
背景情况:
- 类风湿性关节炎 (RA) 患者面临骨折,心血管疾病 (CVD) 和过早死亡的风险增加.
- 双能X射线吸收计 (DXA) 已被公认为用于骨质疏松症管理,但也显示出更广泛的健康评估的潜力.
- 在骨折风险算法中,RA是一个独特的因素,通常会促使DXA扫描用于骨质疏松症评估.
研究的目的:
- 在类风湿性关节炎患者群体中对DXA和心血管疾病现有文献进行范围审查.
- 了解DXA在RA中评估心血管疾病的现状和临床潜力.
主要方法:
- 在Medline和Embase进行了全面的文献搜索.
- 确定了822篇论文,其中包括7项涉及来自7个国家的2038名RA患者的研究.
- 包括的研究设计是截面,纵向和病例对照.
主要成果:
- 所有包括的研究都发现了DXA衍生措施与RA患者的各种心血管参数之间的关联.
- 只有一个研究将临床心血管事件作为结果.
- 在RA群体中关于DXA和CVD的文献有限,但表明有显著的临床潜力.
结论:
- 目前关于DXA在类风湿性关节炎中用于心血管疾病评估的研究对象相对未被探索.
- DXA对评估RA患者心血管风险具有相当大的临床潜力.
- 需要进一步调查,以充分利用DXA技术来管理RA并发症.
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