积极的儿童疫苗接种提醒系统对丹麦疫苗覆盖率和接种率的影响:基于登记的队列研究
Tjede Funk1, Sarah Kristine Nørgaard2, Louise Hallundbæk2
1Department of Infectious Disease Epidemiology and Prevention, Statens Serum Institut, Copenhagen, Denmark; ECDC Fellowship Programme, Field Epidemiology path (EPIET), European Centre for Disease Prevention and Control (ECDC), Stockholm, Sweden.
Vaccine
|March 27, 2025
概括
丹麦的积极的儿童疫苗接种提醒系统改善了疫苗接种覆盖率和主要婴儿免疫接种率. 该系统导致了对结,喉,百日咳,脊髓灰质炎,Hib和MMR疫苗的更高的疫苗接种率.
科学领域:
- 公共卫生 公共卫生
- 免疫接种计划 免疫接种计划
- 儿科疫苗学 儿科疫苗学
背景情况:
- 丹麦于2019年8月推出了积极的儿童疫苗接种提醒系统.
- 该系统旨在提高疫苗接种覆盖率,及时采用必需的婴儿免疫.
研究的目的:
- 评估丹麦积极接种疫苗提醒系统的影响.
- 评估DTaP-IPV/Hib和MMR1疫苗接种覆盖率和接种率的变化.
主要方法:
- 基于登记的回顾性队列研究,比较2018年1月 (控制) 和2022年1月 (干预) 的出生队列.
- 随访包括计划接种疫苗前2周至计划接种疫苗后6周,最后为16.5个月.
- 统计分析包括卡普兰-梅尔曲线,logrank测试和后勤回归来比较疫苗接种状态和时间.
主要成果:
- 在大多数疫苗中,干预队列的计划后6周的疫苗接种率更高.
- 在干预组中,未接种疫苗的儿童显著减少 (1.3%对3.4%),接种疫苗的儿童更多 (88.3%对79.0%).
- 干预组的儿童更有可能按计划接种疫苗,除了第二剂DTaP-IPV/Hib.
结论:
- 积极的疫苗接种提醒系统与四种关键儿童疫苗中的三种疫苗的改善疫苗接种覆盖率有关.
- 该系统还表明,与实施前的时期相比,接种疫苗的速度有点快.
- 积极提醒系统是加强公共卫生免疫工作的宝贵策略.
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