丹麦注意力缺陷/多动障碍的患病率和发病率. 一个基于国家注册的公开队列研究
Simon Grøntved1,2, Kathrine Hald2,3, Christina Mohr-Jensen1,4
1Psychiatry, The North Denmark Region, Aalborg, Denmark.
Acta psychiatrica Scandinavica
|March 27, 2025
概括
由于女性诊断的增加,在丹麦2000-2022年期间,注意力缺陷/多动症 (ADHD) 的患病率和发病率显著增加. 治疗ADHD的药物使用量也增加,甲基化物仍然很常见.
科学领域:
- 神经科学与公共卫生
- 神经发育障碍的流行病学
背景情况:
- 在全球范围内,注意力缺陷/多动症 (ADHD) 患病率和发病率的增加.
- 之前的丹麦ADHD估计存在,但方法上的差异阻碍了时间趋势的评估.
研究的目的:
- 在丹麦 (2000-2022) 一贯计算每年的ADHD患病率和发病率.
- 在同一时期跟踪ADHD药物使用趋势.
主要方法:
- 一个开放的队列研究,利用全国性的丹麦登记数据.
- 通过医院诊断 (ICD-10代码) 或ADHD药物处方定义的ADHD.
主要成果:
- 患有ADHD的患病率从2000年的0.10%上升到2022年的3.03%,影响2.52%的人口.
- 在2022年,18-27岁的人群中,患病率为8.16% (男性) 和6.12% (女性).
- 患有多动症的药物使用增加;甲基化物仍然是主要的药物,但lisdexamphetamine使用量增加.
结论:
- 丹麦的ADHD患病率在过去二十年里稳步升.
- 女性,特别是年轻女性 (2020-2022) 的发病率增加是主要的驱动因素.
- 甲基化物仍然是最常被处方的多动症药物,利斯德胺处方显著增加.
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