普罗特斯 (Proteus vulgaris) 托芬与l-氨酸和l-氨酸的醇-酶复合物的结构和动态

Robert S Phillips1, S Meredith Brown2

  • 1Department of Chemistry, University of Georgia, Athens, GA, 30602, USA; Department of Biochemistry and Molecular Biology, University of Georgia, Athens, GA, 30602, USA.

概括

托英多利酶 (TIL) 酶结构揭示了和压力如何影响其与抑制剂的相互作用. K + 形式显示了多种复合体,而 Na + 形式较慢,压力诱导可逆变化并识别了宝石-胺中间体.

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