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Generation of a Three-dimensional Full Thickness Skin Equivalent and Automated Wounding
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数字双胞胎的开发和校准用于人类皮肤在组织扩张中的生长

Joel Laudo1, Tianhong Han1, Ariel E Figueroa2

  • 1School of Mechanical Engineering Purdue University, West Lafayette, IN, USA.

Acta biomaterialia
|March 27, 2025
PubMed
概括

这项研究首次在组织扩张 (TE) 过程中对人体皮肤生长进行了体内测量,开发了个性化的数字双胞胎,以改善外科手术规划. 有限元模型准确地捕获TE,使用猪数据作为贝叶斯校准的强有力的先验.

关键词:
贝叶斯的校准是贝叶斯的校准.乳腺癌 乳腺癌 乳腺癌乳腺组织机械学计算机械生物学计算机械生物学斯过程替代体儿科重建性手术 儿科重建性手术皮肤的生物力学组织生长和重塑.

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The development of all multicellular organisms starts with the fusion of haploid cells called sperm and egg to form a diploid zygote. A zygote is a totipotent cell that can develop into a complete organism. The zygote undergoes cell division or cleavage to form an 8-cell mass. Until this stage, the cells are spherical, loosely attached, and remain totipotent. Totipotent cells are capable of developing both the embryonic and the extraembryonic tissues. However, as they continue to divide, they...
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