相关实验视频

Updated: May 1, 2026

Heart Dissection in Larval, Juvenile and Adult Zebrafish, Danio rerio
06:43

Heart Dissection in Larval, Juvenile and Adult Zebrafish, Danio rerio

Published on: September 30, 2011

22.6K

网红酸促进了第二个心脏场的增加,并调节了斑马鱼的腹腔大动脉模式

Austin H C Griffin1, Allison M Small1, Riley D Johnson1

  • 1Department of Biology, Miami University, Oxford, OH, 45056, USA.

Developmental biology
|March 27, 2025
PubMed
概括

网红酸 (RA) 信号传递对斑马鱼心脏发育至关重要. 在晚期发育中抑制RA会损害腹腔心肌细胞的增加,并影响流出通道和腹腔大动脉中平滑肌肉细胞的分布.

关键词:
大动脉的大动脉.心脏的发展心脏的发育输出流通道的流出通道雷蒂诺酸是什么意思 雷蒂诺酸是什么意思第二个心脏场.斑马鱼是一种斑马鱼.

更多相关视频

Microbead Implantation in the Zebrafish Embryo05:54

Microbead Implantation in the Zebrafish Embryo

Published on: July 30, 2015

12.4K
Isolation and Characterization of Single Cells from Zebrafish Embryos09:25

Isolation and Characterization of Single Cells from Zebrafish Embryos

Published on: March 12, 2016

15.4K

相关概念视频

G-Protein Gated Ion Channels01:21

G-Protein Gated Ion Channels

GPCRs are primarily responsible for our sense of smell, taste, and vision.  The binding of a sensory stimulus activates GPCR to stimulate effector proteins, many of which are ion channels in the sensory organs. GPCRs modulate the opening and closing of the target ion channels either directly by binding them, or by releasing second messengers that activate these channels. As ions move across the membrane, the membrane potential is altered, which induces an appropriate response.
Sensory...
5.5K
Nitric Oxide Signaling Pathway01:28

Nitric Oxide Signaling Pathway

Nitric oxide (NO), an inorganic gas, acts as a potent second messenger in most animal and plant tissues. NO diffuses out of the cells that produce it and enters the neighboring cells to generate a downstream response. NO synthase (NOS) catalyzes NO production by the deamination of the amino acid arginine. There are three isoforms of NOS. Endothelial cells have endothelial NOS (eNOS), nerve and muscle cells have neuronal NOS (nNOS), and macrophages produce inducible NOS (iNOS) upon exposure...
5.3K
Heart Failure Drugs: Inotropic Agents01:26

Heart Failure Drugs: Inotropic Agents

Positive inotropic agents are commonly used as the first line of treatment for heart failure. One such agent is digoxin, derived from the genus Digitalis, which has been known for centuries but effectively utilized since 1785. However, these cardiac glycosides can have potentially toxic effects due to their mechanism of action, which involves inhibiting Na+/K+-ATPase and increasing contractility. Digoxin is absorbed orally and distributed in various tissues, including the CNS. It has a long...
2.0K
Heart Failure Drugs: Inhibitors of Renin-Angiotensin System01:26

Heart Failure Drugs: Inhibitors of Renin-Angiotensin System

The activation of the sympathetic nervous system and the renin-angiotensin-aldosterone system (RAAS) contributes to cardiac remodeling, and inhibiting the RAAS is a pharmacological target in heart failure management. As a result, neurohumoral modulation is a crucial treatment principle for managing heart failure. This approach involves using medications like ACE inhibitors (ACEIs), angiotensin receptor blockers (ARBs), β-blockers, mineralocorticoid receptor antagonists (MRAs), and neutral...
1.9K
Regulation of Heart Rates01:31

Regulation of Heart Rates

The regulation of heart rate is a complex process controlled by the autonomic nervous system (ANS), hormonal influences, and intrinsic cardiac mechanisms. The ANS has two main components: the sympathetic nervous system (SNS) and the parasympathetic nervous system (PNS).
The SNS increases heart rate through the release of norepinephrine and epinephrine, which act on beta-1 adrenergic receptors in the heart. This action increases the rate of depolarization in the sinoatrial (SA) node, the heart's...
6.0K
Heart Failure II: Pathophysiology01:29

Heart Failure II: Pathophysiology

Systolic Heart Failure and Compensatory MechanismsSystolic heart failure (also termed HFrEF, Heart Failure with Reduced Ejection Fraction) is the most prevalent type of heart filure. It results in a decreased volume of blood being pumped from the ventricle. The aortic arch and carotid sinuses have baroreceptors that detect reduced blood pressure, triggering the sympathetic nervous system (SNS) to release epinephrine and norepinephrine. Initially, this response aims to boost heart rate and...
1.9K