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Updated: Jun 12, 2025

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低剂量Taxol会在活跃呼吸的癌细胞中引起线粒体功能障碍

Rozhin Penjweini1, Katie A Link1, Shureed Qazi1

  • 1Laboratory of Advanced Microscopy and Biophotonics, National Heart, Lung, and Blood Institute (NHLBI), NIH, Bethesda, Maryland, USA.

The Journal of biological chemistry
|March 27, 2025
PubMed
概括

塔克索尔对氧化性癌细胞中的线粒体产生不利影响,增加活性氧物种和细胞染色体c的释放,同时降低ATP的产生和氧化酸化. 在非癌细胞中没有观察到这些变化.

关键词:
奥克斯福斯 (OXPHOS) 是一个低剂量Taxol的使用方法线粒体的新陈代谢形态学和动力学.

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