人工智能,制药开发和双重用途研究令人担忧:呼吁采取行动
Christopher Bobier1, Daniel J Hurst2, John Obeid3
1Central Michigan University College of Medicine, Mount Pleasant, Michigan, USA cabobier@gmail.com.
Journal of medical ethics
|March 27, 2025
概括
药品开发中的人工智能 (AI) 提出了新的双重用途研究关注 (DURC) 挑战. 本研究探讨了这些新出现的风险,以及对人工智能驱动药物发现的更新治理和指导的需要.
科学领域:
- 生物技术是生物技术.
- 制药科学 制药科学
- 人工智能的人工智能
背景情况:
- 双重用途研究 (DUR) 和双重用途关注的研究 (DURC) 已经引起了大量的关注,因为它们的潜在利益和危害.
- 人工智能 (AI) 越来越多地融入制药开发中,这为DURC带来了新的考虑.
研究的目的:
- 探索与制药开发中的人工智能 (AI) 相关的新出现的挑战,特别是涉及双重用途关注的研究 (DURC).
- 突出目前行业和政府指导管理人工智能驱动的药物发现中的DURC的差距.
主要方法:
- 在制药开发中对人工智能应用的概念分析.
- 审查现有的DURC治理框架.
- 识别AI在这个领域带来的潜在风险和挑战.
主要成果:
- 人工智能越来越多地被认为是制药行业的双重用途研究 (DURC) 的贡献者.
- 显著缺乏特定的行业和政府指导,以应对人工智能在制药开发中所带来的独特挑战.
- 人工智能的快速发展需要采取积极的方法来理解和减轻药物发现中的潜在错误应用.
结论:
- 人工智能在制药开发中的应用代表了双重用途研究关注 (DURC) 治理的新前沿.
- 需要紧急制定全面的行业和政府指导方针,以解决AI在药物发现中的安全和安全影响.
- 需要进一步的研究,以建立在制药行业负责任的人工智能实施的最佳实践.
相关概念视频
Issues And Trends In Healthcare Delivery System
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Drug Regulation
Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...
Preclinical Development: Overview
Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
Prescription, Nonprescription and Orphan Drugs
Prescription drugs require a prescription from a medical practitioner and can only be obtained from a pharmacy. They have many applications, including treating pain, anxiety, and hypertension.
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
The misuse and addiction to prescription drugs is a growing problem that can affect people of all age groups, specifically teenagers. This can happen when prescription medications are used in ways not intended by the prescriber, such as taking someone else's prescription or using medication for...
Drug Control Governance: Regulatory Bodies and Their Impact
Drug control governance involves the oversight and regulation of pharmaceuticals to ensure their safety and efficacy while preventing illegal drug use and trafficking. Regulatory bodies, including the US Food and Drug Administration (FDA) and the European Union's European Medicines Agency (EMA), play a central role in this process. These agencies evaluate the safety and efficacy of drugs before they can be marketed. They fund clinical trials and assess the benefits and risks associated with a...
Pharmaceutical Poisoning: Potential Scenarios
Pharmaceutical poisoning can occur through various channels, impacting an estimated 2 million hospitalized patients in the U.S. annually with serious adverse drug responses. These scenarios encompass both therapeutic uses, such as drug toxicity, where even standard dosages can lead to severe central nervous system depression, and non-therapeutic exposures, including accidental ingestion by children, and environmental and occupational exposures.Unintentional poisonings often involve exploratory...
