钻石 - - 一个糖尿病自我管理干预严重精神疾病患者:个人随机对照多中心试验的协议
Grace Catherine O'Carroll1, Jennifer V E Brown2, Claire Carswell1
1Department of Health Sciences, University of York, York, UK.
BMJ open
|March 27, 2025
概括
这项研究评估了针对严重精神疾病 (SMI) 和2型糖尿病 (T2DM) 患者的新型糖尿病自我管理计划. 钻石试验评估了其在改善健康结果和降低成本方面的有效性.
科学领域:
- 临床试验 临床试验
- 公共卫生 公共卫生
- 心理健康研究 心理健康研究
背景情况:
- 2型糖尿病 (T2DM) 在患有严重精神疾病 (SMI) 的人群中明显更为普遍.
- 有效的糖尿病自我管理支持对于改善这一群体的临床结果至关重要.
- 钻石试验通过一种新的,共同设计的程序来解决这一需求.
研究的目的:
- 评估DIAMONDS支持的糖尿病自我管理计划的临床和成本效益.
- 为了比较钻石干预与T2DM患者SMI的通常治疗.
- 评估该计划对糖化血红蛋白 (HbA1c) 和其他健康指标的影响.
主要方法:
- 一个多中心,双臂,个人随机对照试验,涉及380名SMI和T2DM参与者.
- 参与者被随机分配到DIAMONDS干预 (6个月的指导,工作簿,应用程序) 或通常的治疗中.
- 主要结局:12个月的HbA1c差异;次要结局:身体/精神健康,并发症,体力活动.
主要成果:
- (由于研究正在进行/招聘,结果尚未提供)
- 主要结果 (HbA1c) 和次要结果将在随机化后12个月进行评估.
- 经济和过程评估将补充临床发现.
结论:
- 钻石试验正在调查针对弱势群体糖尿病自我管理的量身定制方法.
- 预计研究结果将为SMI患者的T2DM管理提供最佳实践信息.
- 该研究强调共同设计和全面的结果评估.
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