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轴性脊髓关节炎中关节外表现的负担:摩洛哥单中心研究

Khaoula Tahir¹, Nessrine Akasbi¹, Imane El Mezouar¹

¹Rheumatology Department, Hassan II University Medical Center Fez, Faculty of Medicine and Pharmacy and Dentistry of Fez, University Sidi Mohammed Ben Abdellah, Fez, Morocco.

Musculoskeletal care

|March 27, 2025

概括

像IBD和AAU这样的关节外表现 (EAM) 在轴性脊柱关节炎 (axSpA) 中很常见. EAMs显著恶化疾病特征和患者报告的结果,强调它们在axSpA管理中的重要性.

科学领域:

类风湿病学类风湿病学
免疫学免疫学免疫学
临床医学临床医学

背景情况:

轴性脊椎关节炎 (axSpA) 是一种慢性炎症性疾病,其特征是不同的临床表现.
关节外表现 (EAMs),包括急性前膜炎 (AAU),炎症性肠病 (IBD) 和牛皮,在axSpA患者中很常见.

研究的目的:

评估EAM对axSpA患者疾病特征和临床结果的影响.
确定与axSpA.中EAM存在相关的因素.

主要方法:

一项涉及400名根据ASAS 2009标准诊断的axSpA患者的横截面研究.
在12年的时间里,axSpA患者与没有EAM之间的疾病特征的比较.

主要成果:

在 axSpA 患者中,有30.3%的人患有EAM,其中IBD (18.5%) 和AAU (12.5%) 是最常见的.
患有EMS的患者表现出更长的疾病持续时间,增加脊柱疼痛和硬,更高的疾病活性和更差的身体功能.
身体功能恶化 (BASFI) 被确定为与EMS相关的主要独立因素.

结论:

EAMs,特别是IBD和AAU,在axSpA中普遍存在,并显著影响临床结果.
在axSpA患者的综合管理中,EMS的存在需要仔细考虑.
了解EAM的影响对于改善患者报告的措施和axSpA的整体疾病管理至关重要.

关键词:

剧烈的前性脑膜炎.轴性脊椎关节炎轴性脊椎关节炎关节外表现的表现.炎症性肠病是一种炎症性肠病.牛皮是一种牛皮.

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