结直肠作为结直肠癌的初始表现:系统性审查
Fatemeh Shahabi1, Abbas Abdollahi1, Mahdieh Zarif-Sadeghian1
1Endoscopic and Minimally Invasive Surgery Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
结直肠脱落可能是结直肠癌的最初迹象,特别是在65岁以上的女性中. 这一系统性审查强调了直肠出血和便秘是常见的伴随症状,敦促对高危患者进行进一步调查.
科学领域:
- 胃肠病学 胃肠病学
- 在瘤学瘤学.
- 公共卫生 公共卫生
背景情况:
- 结肠直肠癌的发病率正在上升,这对公众健康构成了重大挑战.
- 作为结直肠癌的初始表现,直肠脱落需要进一步调查.
研究的目的:
- 系统地审查结直肠癌患者最初呈现直肠.
- 确定这些病例的人口,临床和病理特征.
主要方法:
- 通过Web of Science,PubMed和Scopus识别的病例报告的系统审查.
- 遵守系统审查和元分析 (PRISMA) 准则的首选报告项目,用于数据提取.
主要成果:
- 包括31个病例报告,超过一半的患者是65岁以上的女性 (平均年龄64±17.9岁).
- 大多数癌症 (64.5%) 起源于直肠或直肠-西格蒙区域.
- 结直肠出血和便秘是最常见的伴随症状.
结论:
- 结直肠脱落可能是结直肠癌的初始表现,特别是在老年女性中.
- 自2015年以来,越来越多的病例报告表明了上升的趋势.
- 对于呈现直肠脱落而没有明显诱导同伴瘤的因素的患者,建议对其进行进一步的治疗.
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