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Updated: Jun 15, 2026

Mapping the Structure-Function Relationships of Disordered Oncogenic Transcription Factors Using Transcriptomic Analysis
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bHLH TCF4蛋白质的分子特性作为一个内在无序的枢纽转录因子

Nikola Sozańska1, Barbara P Klepka2, Anna Niedzwiecka2

  • 1Department of Biochemistry, Molecular Biology and Biotechnology, Faculty of Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, Wrocław, 50-370, Poland.

Cell communication and signaling : CCS
|March 28, 2025
PubMed
概括

转录因子4 (TCF4) 是一种大型,内在无序的蛋白质. 它的bHLH域将其固定在DNA上,而无序的区域与其他伙伴相互作用,表明其作为枢纽转录因子的作用.

关键词:
基本螺旋-循环-螺旋 (bHLH) 的基本螺旋埃弗鲁西盒子 (E盒)枢纽蛋白质是一个枢纽蛋白质.免疫球体蛋白转录因子2 (ITF2)本质上有障碍的蛋白质 (IDP)本质上是无序的区域 (IDRs).在SL3-3增强因子2 (SEF2) 中.转录因子4 (TCF4) 是一种转录因子.转录因子 (TFs) 是一种转录因子.

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