社区药剂师对约旦抗菌药物处方的反应:一个跨部门调查
Ma'en Al-Odat1, Shadi Mustafa2, Yousef Al-Hajaya3
1Department of Medical Laboratory Science, Faculty of Allied Medical Science, Mutah University, Karak 61710, Jordan.
Antibiotics (Basel, Switzerland)
|March 28, 2025
概括
约旦的药剂师对抗生素处方和抗菌药物管理充满信心,但面临着获取信息的挑战,需要更好的决策支持工具. 他们经常在没有处方的情况下为常见感染提供抗生素,强调需要改善抗菌素滥用教育.
科学领域:
- 药理学 药理学是指药理学的学科.
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 社区药剂师通过非处方药 (OTC) 系统性抗生素处方的全球增长有助于抗生素耐药性.
- 药房中抗生素的可获得性对国际努力打击抗生素耐药细菌提出了重大挑战.
- 了解药剂师的做法对于制定有效的抗菌药物管理策略至关重要.
研究的目的:
- 调查约旦社区药剂师之间的抗生素选择和OTC抗生素处方模式.
- 评估药剂师的知识,信息来源和与抗菌素处方相关的挑战.
- 评估约旦社区药房中抗菌药物管理实践的程度.
主要方法:
- 在约旦,对244名社区药剂师进行了一项标准化的在线调查.
- 该调查涵盖了包括信息来源,抗微生物药物类别,无处方药和药剂师知识在内的领域.
- 数据分析的重点是处方习惯,常见的感染治疗,以及对抗生素信息获取的感知挑战.
主要成果:
- 药剂师对抗生素处方表示信心,并利用各种工具来提高技能.
- 抗生素是最常见的不需处方的抗微生物药物,特别是用于喉,泌尿道,胸部感染和中耳炎.
- 常规处方的抗生素包括用于喉感染的青素,用于尿路感染的诺基诺,用于未指定的感染的头素和用于中耳炎的类抗生素. 许多药剂师报告说,很难获得抗生素信息,但很高的百分比旨在教育患者关于抗菌药物的风险.
结论:
- 约旦社区药剂师表现出遵守临床指南,并参与抗菌药物管理.
- 有对OTC抗微生物药物的需求,并且在药剂师中承认缺乏决策支持工具.
- 药剂师在解决抗微生物药物的滥用方面发挥着关键作用,强调需要加强患者教育和提供可访问的处方信息.
相关概念视频
Antibiotic Selection
Overview
Pharmacovigilance
Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
This process, termed pharmacovigilance, aims to detect, evaluate, and minimize harmful effects related to medication use. The data collection for pharmacovigilance depends on spontaneous reporting systems, where healthcare professionals or patients voluntarily report suspected ADRs.
In some cases, there...
Analysis of Population Pharmacokinetic Data
Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
Antimicrobial Effectiveness
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
Development of Antibiotic Resistance
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
Clinical Significance of Antibiotic Resistance
Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...


