ICD-10代码用于识别行政数据中与抗生素相关的不良药物事件
Hannah Lishman1, Amber Cragg2, Erica Chuang1
1BC Centre for Disease Control, Vancouver, BC V5Z 4R4, Canada.
Antibiotics (Basel, Switzerland)
|March 28, 2025
概括
这项研究开发了一份诊断代码清单,以识别与抗生素相关的不良药物事件 (ADEs),导致住院治疗. 这种方法改善了在初级保健中对抗生素使用造成的伤害的跟踪.
科学领域:
- 药物监督 药物监督 药物监督
- 医疗信息学 医疗信息学
- 药品安全 药品安全
背景情况:
- 抗生素在初级保健中被广泛使用,造成药物不良反应 (ADEs) 的风险.
- 准确识别与抗生素相关的ADEs对于患者安全和医疗保健管理至关重要.
- 现有的行政数据可能无法完全捕捉与抗生素相关的危害范围.
研究的目的:
- 为需要急性护理的抗生素相关的ADEs创建一个全面的诊断代码列表.
- 加强对监测药物安全的行政数据的利用.
- 促进研究抗生素相关不良事件的负担.
主要方法:
- 利用先前公布的不良药物事件 (ADE) 代码,将住院治疗与先前的抗生素处方联系起来.
- 基于住院前一个月内服用抗生素的过代码.
- 临床专家独立审查了抗生素关联的代码,并使用卡帕分数计算了评估者之间的可靠性.
主要成果:
- 总共有695个国际疾病分类第10次修订 (ICD-10) ADE代码被确定为最近暴露于抗生素.
- 其中,72个代码被归类为可能与抗生素相关,68个可能相关,555个不太可能相关.
- 建立了一种可靠的方法来分类与抗生素相关的ADEs.
结论:
- 一个经过验证的ICD-10代码列表已经开发出来,用于识别严重的抗生素相关的ADEs.
- 这种方法可以更好地利用行政数据来捕获和研究与抗生素相关的危害.
- 改善对ADEs的监测可以为更安全的抗生素处方实践提供信息.
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