混合方法方法:临床消费者多样性对临床试验招生的影响
Angelica Sanchez1, Christina M Vidal1, Noé Rubén Chávez2
1City of Hope Comprehensive Cancer Center, Duarte, CA 91010, USA.
Cancers
|March 28, 2025
概括
消费者的种族和种族对临床试验多样性的影响很大. 彩色女性 (WOC) 参与者在决定参加乳腺癌试验时更有可能考虑同意者的种族和社区代表性.
科学领域:
- 临床研究伦理学
- 在健康方面存在差异.
- 医学社会学 医学社会学
背景情况:
- 临床试验旨在使所有人群受益,但许多癌症中心都在努力实现公平的参与者积累.
- 美国国家癌症研究所要求根据区域癌症负担进行比例招生.
- 获得同意的个人的特点可能会影响参与者的决定.
研究的目的:
- 调查同意者的社会文化背景如何影响潜在参与者加入临床试验的决定.
- 检查消费者种族,种族和语言对试验招生的影响.
主要方法:
- 采用混合方法方法来研究消费者对参与试验的影响.
- 在乳腺诊所接触了205名妇女;完成了181项调查.
- 参与者被分为北欧人,非西班牙裔白人 (NE White) 或有色人种妇女 (WOC),包括亚洲人,黑人,西班牙裔/拉丁裔或美洲原住民.
主要成果:
- 关于消费者特征在注册决定中的重要性,出现了显著的差异.
- 0%的NE白人参与者认为消费者种族很重要,相比之下,WOC参与者的比例为11% (p=0.0009).
- 12%的WOC参与者认为消费者"看起来像我社区的人"很重要,相比之下,0%的NE白人参与者 (p=0.0004).
结论:
- 消费者的种族和种族是影响临床试验多样性的关键因素.
- 需要进一步的研究来证实这些发现在不同人群中的普遍性.
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