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整合人工智能和生物信息学方法来识别破坏性STAT1变体,影响蛋白质稳定性和功能

Ebtihal Kamal1, Lamis A Kaddam2, Mehad Ahmed1

  • 1Department of Basic Medical Sciences, College of Medicine, Prince Sattam bin Abdulaziz University, Al Kharj 16278, Saudi Arabia.

Genes
|March 28, 2025
PubMed
概括

这项研究确定了信号转换器和转录1激活器 (STAT1) 基因中的六种有害单核酸多态 (SNPs),预测它们对蛋白质结构和功能的影响. 这些发现为识别与疾病相关的STAT1变异提供了实验方法的经济有效替代方案.

关键词:
美国国家统计局 (STAT1)这是自身免疫力.在的中.信号通道的信号通道.一个核酸的多态性.

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