多发性硬化症的认知运动合:时间年龄和体力活动是否重要?
Brenda Jeng1, Peixuan Zheng1, Robert W Motl1
1Department of Kinesiology and Nutrition, University of Illinois Chicago, Chicago, IL 60612, USA.
Brain sciences
|March 28, 2025
概括
认知-运动合,思维和运动之间的联系,在多发性硬化症 (MS) 患者中持续存在,无论年龄或身体活动如何. 在MS中认知功能和运动技能之间的这种联系是关键的发现.
科学领域:
- 神经科学是一个神经科学.
- 康复医学 康复医学 康复医学
- 临床神经学 临床神经学
背景情况:
- 多发性硬化症 (MS) 经常导致认知和身体障碍.
- 认知-运动合,即认知和运动功能之间的关系,在MS中得到了记录.
- 在控制年龄和体力活动时,对这种合存在有限的研究.
研究的目的:
- 研究患有多发性硬化症的人的认知运动合.
- 为了确定这种合是否受到时间学年龄和身体活动水平的影响.
主要方法:
- 290名多发性硬化症患者 (年龄在22-77岁之间) 参与了这项研究.
- 使用符号数字模式测试 (SDMT) 和加利福尼亚语言学习和记忆测试第二版 (CVLT-II) 评估认知功能.
- 通过6分钟步行测试和25英尺步行测试来评估运动功能.
- 在7天内使用加速度计测量中度至强度体力活动 (MVPA).
主要成果:
- 两变相关性显示了认知和运动功能之间的中度至强度关联 (r范围:0.433-0.459).
- 在控制共变量后,线性回归证实了SDMT (β范围:0.139-0.145) 和CVLT-II (β范围:0.125-0.135) 的认知运动合.
- 即使考虑到年龄和MVPA (SDMT:β=0.119;CVLT-II:β范围:0.115-0.124),这种合仍然显著.
结论:
- 认知运动合是MS患者的强有力的发现.
- 这种关系独立于时间表年龄和身体活动水平.
- 需要进一步的研究来了解MS相关功能障碍的机制并制定管理策略.
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