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Updated: Jul 16, 2026

Selective Depletion of Microglia from Cerebellar Granule Cell Cultures Using L-leucine Methyl Ester
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莱科林预治疗通过抑制NF-κB酸化来缓解脑性缺血后的微质炎症

Wuyan Zheng1, Wanyu Wu1, Yuhan Li1

  • 1Dr. Neher's Biophysics Laboratory for Innovative Drug Discovery, State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau SAR, China.

Brain sciences
|March 28, 2025
PubMed
概括

莱科林 (LYC) 通过抑制NF-κB通路,减少缺血性中风 (IS) 模型中的神经炎症,显示出抗炎作用. 这表明LYC可能是一种潜在的辅助治疗,以改善IS的预后.

关键词:
澳大利亚MCAOO通过NF-B路径.这是一种炎症炎症炎症炎症.缺血性中风 中风莱科林 (Lycorine) 是一种类型的

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相关概念视频

NF-κB-dependent Signaling Pathway02:26

NF-κB-dependent Signaling Pathway

The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
NF-κB-dependent Signaling Mechanism
The heterodimer of NF-κB...