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Updated: Jun 18, 2026

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis
08:34

Mechanism of Regulation of Adipocyte Numbers in Adult Organisms Through Differentiation and Apoptosis Homeostasis

Published on: June 3, 2016

CSN-CRL复合物:新型脂肪生成调节剂

Dawadschargal Dubiel1, Michael Naumann1, Wolfgang Dubiel1

  • 1Institute of Experimental Internal Medicine, Medical Faculty, Otto von Guericke University, Leipziger Str. 44, 39120 Magdeburg, Germany.

Biomolecules
|March 28, 2025
PubMed
概括

构成性光形生成9信号体 (CSN) 和其变体通过控制细胞循环停止和蛋白质降解来调节脂肪生成. 在CSN-CRL复合体中的故障与肥胖有关,需要治疗策略.

关键词:
COP9信号体 (CSN) 是一个信号体.脂质生成 (adipogenesis) 是一种细胞循环抑制剂 p27KIPIP 细胞循环抑制剂库林-RING-ubiquitin连接酶 (CRLs) 是一种可靠的方法.肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖 肥胖治疗治疗治疗治疗治疗治疗

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