相关实验视频

Updated: May 5, 2026

Assessment of Child Anthropometry in a Large Epidemiologic Study

Assessment of Child Anthropometry in a Large Epidemiologic Study

Published on: February 2, 2017

探索内脏脂肪作为儿童和青少年心脏代谢风险的查标记

Xia Wang¹, Hong Cheng², Jingfan Xiong³

¹Center for Non-Communicable Disease Management, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing 100035, China.

Children (Basel, Switzerland)

|March 28, 2025

概括

新的内脏脂肪区域 (VFA) 切断线有效地识别儿童和青少年的心脏代谢风险 (CMR). 这些经过验证的VFA查工具有助于对高血压和脂质失调等疾病进行早期干预.

科学领域:

儿科儿科儿科
心脏病学心脏病学
代谢健康代谢健康

背景情况:

心脏代谢风险 (CMR) 是儿童和青少年日益关注的问题.
内脏脂肪面积 (VFA) 是CMR的一个关键指标,但缺乏标准化查切线.
准确识别CMR对于及时干预和预防长期健康后果至关重要.

研究的目的:

建立和验证特定于年龄和性别的内脏脂肪区域 (VFA) 截止值,用于确定儿科患者心脏代谢风险 (CMR).
评估这些关键CMR指标的VFA截止值的预测性能.
评估与高VFA水平相关的CMR纵向风险.

主要方法:

一项横截面研究从8133名参与者中得出了特定于年龄和性别的VFA切线.
一个由10805个个体组成的纵向队列验证了衍生的VFA切断值.
使用后勤回归和ROC曲线分析来评估CMR的预测性能和相对风险 (RR).

主要成果:

在男孩和女孩中,VFA的第75个百分位是查高血压,高血糖,血脂不良和CMR聚类的最佳水平 (除了女孩的高血糖,其中第80个百分位是最佳).
纵向验证证实,在超过VFA切线的个体中,CMR风险显著更高 (男孩RR 1.33-3.89,女孩RR 1.63-3.16).
体重正常,VFA高的男孩显示CMR风险增加,突出显示VFA在BMI之外的重要性.

结论:

确定的年龄和性别特定的VFA切线是查中国儿童和青少年中CMR的有效工具.
这些VFA切线有助于早期识别和干预心脏代谢异常.
这些发现强调了VFA测量在儿科风险评估中的有用性,无论整体体重状况如何.

关键词:

青少年青少年青少年心脏代谢风险心脏代谢风险孩子们的孩子们的孩子们的孩子们.切断的切断,切断的切断.肥胖肥胖肥胖肥胖肥胖肥胖肥胖肥胖内脏脂肪区域的内脏脂肪区域.

更多相关视频

Assessment of Human Adipose Tissue Microvascular Function Using Videomicroscopy

Assessment of Human Adipose Tissue Microvascular Function Using Videomicroscopy

Published on: September 29, 2017

Isolation of Viable Adipocytes and Stromal Vascular Fraction from Human Visceral Adipose Tissue Suitable for RNA Analysis and Macrophage Phenotyping

Isolation of Viable Adipocytes and Stromal Vascular Fraction from Human Visceral Adipose Tissue Suitable for RNA Analysis and Macrophage Phenotyping

Published on: October 27, 2020

相关概念视频

Cholesterol: Significance and Regulation

Cholesterol: Significance and Regulation

Although not a source of energy, cholesterol plays a significant role as a foundational structure for bile salts, steroid hormones, and vitamin D, as well as being a crucial component of plasma membranes. Approximately 15% of blood cholesterol is derived from our diet, with the remainder synthesized from acetyl CoA by the liver and intestines. Cholesterol is eliminated from the body through its conversion into bile salts, which are eventually discarded in the feces.
Considering cholesterol and...

Obesity

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...