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Updated: Aug 10, 2026

High Content Screening Analysis to Evaluate the Toxicological Effects of Harmful and Potentially Harmful Constituents (HPHC)
11:38

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Published on: May 10, 2016

通过HPLC-MS/MS进行的斯基桑德林B的临床前并发毒动力学研究

Sanwen Li1, Qing Shao2, Hongqun Qiao1

  • 1School of Pharmaceutical Sciences, Nanjing Tech University, Nanjing, China.

Biomedical chromatography : BMC
|March 28, 2025
PubMed
概括

这项研究调查了26周内在老鼠和狗身上施山德林B (Sch B) 的毒动力学. 结果显示了大鼠的性别差异和狗的剂量依赖性积累,为未来的人类风险评估提供了信息.

关键词:
通过HPLC-MS/MS进行.斯基桑德林 B 类型同时进行的毒性动因学研究.

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相关概念视频

High-Performance Liquid Chromatography: Types of Detectors01:15

High-Performance Liquid Chromatography: Types of Detectors

The role of the detectors in High-Performance Liquid Chromatography (HPLC) is to analyze the solutes as they exit from the chromatographic column. The detector recognizes the solute's property and generates corresponding electrical signals, which are converted into a readable graph of the detector's response versus elution time called a chromatogram at the computer. There are several types of HPLC detectors, each with its own advantages and limitations, depending on the analyte properties and...