头癌患者自杀的危险因素:系统性审查和元分析
Sami I Nassar1, Ryan A Durgham1, Shaun A Nguyen1
1Department of Otolaryngology-Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina, USA.
Head & neck
|March 28, 2025
概括
头癌患者面临着明显更高的自杀风险. 非西班牙裔种族和男性性别等特定因素会增加这种风险,而黑人,西班牙裔或女性则会降低这种风险.
科学领域:
- 在瘤学瘤学.
- 精神病学是一个精神病学.
- 流行病学 流行病学
背景情况:
- 头癌 (HNC) 患者的自杀风险明显增加.
- 了解这一群体内的特定风险因素对于有针对性的干预至关重要.
研究的目的:
- 系统地审查和分析被诊断为头癌的患者中自杀风险因素.
- 将HNC患者的自杀风险与非HNC癌症患者和普通人群进行比较.
主要方法:
- 对数据库进行了全面的文献审查,持续到2024年6月.
- 对比例和相对风险 (RR) 的元分析是根据患者变量分层的数据进行的.
- 包括21项研究,涵盖超过160万HNC患者和超过1680万非HNC癌症患者.
主要成果:
- 与非HNC癌症患者 (RR 2.369) 和普通人群 (RR 26.991) 相比,HNC患者的自杀风险明显更高.
- 增加的风险与非西班牙裔种族 (RR 3.773),男性性别 (RR 2.721),口腔 (RR 1.241) 或喉 (RR 1.182) 癌症相关.
- 相反,认定自己是黑人 (RR 0.316),西班牙裔 (RR 0.265) 或女性 (RR 0.367) 与自杀风险降低有关. 除了喉癌研究,这些人口统计学效应被放大了.
结论:
- 与其他癌症患者群体相比,头癌患者面临的自杀风险大幅增加.
- 喉癌似乎可以缓解其他人口统计学变量对HNC人口中自杀风险的影响.
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