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针对卵巢储量下降患者大脑活动的影响:休息状态功能磁共振成像研究
Bai Tianyu1, Yang Jiaen2, Yin Liang3
1Department of Acupuncture, Moxibustion and Massage, Shandong Provincial Third Hospital, Shandong University, Jinan 250031, China.
概括
卵巢储备 (DOR) 的减少与大脑活动的改变有关,特别是在前部区域. 针可以帮助使这种活动正常化,并改善DOR患者的大脑连接.
科学领域:
- 神经科学是一个神经科学.
- 生殖医学 生殖医学
- 医疗成像医学成像
背景情况:
- 减少卵巢储备 (DOR) 影响女性的生殖健康.
- 大脑功能变化可能与DOR相关.
- 休息状态功能磁共振成像 (rs-fMRI) 是研究大脑活动的关键工具.
研究的目的:
- 使用rs-fMRI对DOR患者的大脑区域变异进行研究,与使用rs-fMRI的健康对照 (HC) 相比.
- 评估针对DOR患者大脑活动的直接影响.
主要方法:
- 在16名DOR患者和17名HC患者身上进行了rs-fMRI扫描.
- 低频波动幅度 (ALFF) 分析发现了大脑区域的差异.
- 功能连接 (FC) 分析检查了针后的大脑网络变化.
主要成果:
- 与HC相比,DOR患者在左下部/中部状回环中显示ALFF增加,在双边上部/中部前部回环和左下部前部回环中显示ALFF减少.
- 针在DOR患者的左上额头,中额头和补充运动区域增加了ALFF.
- 针术后,左上额头和双边皮/舌头之间观察到增强的功能连接.
结论:
- DOR患者在特定的大脑区域表现出异常的神经活动,包括上额头 (SFG),中额头 (MFG) 和下额头 (IFG).
- 针干预似乎调节了SFG活动,将其推向正常水平.
- 针在DOR患者中增强了SFG与双边状和舌环的功能连接.
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