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Updated: Jul 19, 2026

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Published on: April 4, 2018

血生物标志物轨迹:AD遗传风险和临床进展的影响

Corinne Pettigrew1, Anja Soldan1, Jiangxia Wang2

  • 1Department of Neurology The Johns Hopkins University School of Medicine Baltimore Maryland USA.

Alzheimer's & dementia (Amsterdam, Netherlands)
|March 28, 2025
PubMed
概括

认知正常个体的长度血生物标志物变化表明,阿波利波蛋白E (APOE) ε4载体显示出改变的粉样蛋白β和增加的酸化和GFAP. 这些标志物预测了临床前阿尔茨海默病 (AD) 的认知衰退.

关键词:
阿尔茨海默病的疾病阿尔茨海默病的疾病.亚脂蛋白 E 是一种非脂蛋白 E.基于血液的生物标志物在认知上没有受损,没有受损.在纵向的长度上.中年人 中年人血生物标志物 血生物标志物多基因风险评分多基因风险评分.

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