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Updated: May 10, 2026

Experimental Strategies to Bridge Large Tissue Gaps in the Injured Spinal Cord after Acute and Chronic Lesion
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Published on: April 5, 2016

质性痕:在修复运动路径方面是否可以穿透?

Tetsuji Sekiya1,2, Matthew C Holley3

  • 1Department of Otolaryngology-Head and Neck Surgery, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Cell transplantation
|March 28, 2025
PubMed
概括

在脊髓损伤 (SCI) 后恢复运动功能是一项挑战. 将细胞移植到质痕的亲再生基底膜 (BM) 表面可以通过绕过痕核心来增强运动通路的再生.

关键词:
轴突再生的重生作用底层膜的底层膜.细胞传递细胞的交付.皮质脊椎管道的皮质脊椎管道.状痕是状痕的一种.

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In the CNS, neurogenesis, the birth of new neurons from stem cells, is limited to the hippocampus in adults. In other regions of the brain and spinal cord, neurogenesis is almost non-existent due to inhibitory influences from neuroglia, especially oligodendrocytes, and the absence of growth-stimulating cues. The myelin produced by oligodendrocytes in the CNS inhibits neuronal regeneration. Furthermore, astrocytes proliferate rapidly after neuronal damage, forming scar tissue that physically...