夜间透静性低血压与早期和中度正常张力玻璃眼中中心视野缺陷有关
Sung Il Im1, Changmin Cha2, Sangjoon Lee2
1Division of Cardiology, Department of Internal Medicine, College of Medicine, Kosin University, Busan, Korea.
概括
低夜间透静血压与正常张力玻璃眼 (NTG) 患者中最中心视野缺陷有关. 管理夜间透析性低血压可能是预防NTG视力损失的可修改风险因素.
科学领域:
- 眼科医生 眼科 眼科
- 心血管健康 心血管健康
- 玻璃眼研究研究 玻璃眼研究
背景情况:
- 晚间低血压的玻璃眼患者面临视野缺陷的风险增加.
- 夜间透静低血压是正常张力玻璃眼 (NTG) 中最中心视野缺陷 (CMVFD) 的独立危险因素.
- 低平均夜间透气血压是CMVFD的潜在可修改的风险因素.
研究的目的:
- 调查系统血压相关的血液动力学指数与最中心视野缺陷 (CMVFD) 之间的关联.
- 为了检查早期和中度正常张力玻璃眼 (NTG) 的患者.
主要方法:
- 一项对36名患有CMVFD的早期至中度NTG患者的36只眼睛的横截面研究.
- 在295名NTG患者中利用了24小时的门诊血压监测 (ABPM).
- 组之间比较血液动力学变量和眼科检查结果.
主要成果:
- 多变量逻辑回归确定了夜间平均透析血压与CMVFD独立相关 (OR 0.877;P=.037).
- 单变量分析显示CMVFD与24小时平均透气血压,夜间平均静脉血压,夜间平均透气血压和体重之间的关联.
- 在杯与盘的比率,模式标准偏差和视网膜神经纤维层厚度中观察到显著差异.
结论:
- 中部最多视野缺陷 (CMVFD) 在一些早期和中度NTG患者中发生.
- 低夜间透析血压 (夜间透析低血压) 与CMVFD独立相关.
- 在NTG患者的全身管理中,应考虑夜间透气性低血压.
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